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Summary: Doege-Potter syndromeis a paraneoplastic syndrome characterized by nonislet cell tumor hypoglycemia due to a solitary fibrous tumor, which produces insulin-like growth factor II. In this report, we present the case of a 67-year-old male with recurrent and refractory hypoglycemia due to DPS successfully treated with imatinib. He initially presented with neuroglycopenic symptoms and dyspnea secondary to a giant tumor in the left hemithorax, which was totally resected. During follow-up, 7 years later, he presented with thoracoabdominal tumor recurrence associated with severe hypoglycemia and underwent subtotal tumor resection, with a subsequent improvement of symptoms. The following year, he had a recurrence of his intra-abdominal tumor, which was unresectable, associated with severe hypoglycemia refractory to dextrose infusion and corticosteroids, thus receiving imatinib with a favorable response. The clinical presentation, diagnostic approach, progression of the disease, and response to treatment with imatinib in the management of a patient with large, recurrent, and unresectable mesenchymal tumors with insulin-like growth factor-2 secretion causing hypoglycemiahighlight the importance of this case report. Learning points: Doege-Potter syndrome (DPS) is a rare cause of tumoral hypoglycemia of non-pancreatic origin. Some malignant or benignant neoplasms have ectopic secretion of insulin-like growth factor-2. Total surgical removal is the principal treatment in patients with DPS. Tyrosine kinase inhibitors management in DPS may contribute to improved tumor control in patients with unresectable tumors and severe hypoglycemia.
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Introducción: En la actualidad no hay estudios que evalúen específicamente el estado de las revistas biomédicas peruanas sobre la base de criterios como el uso de softwares de proceso editorial o el tipo de artículo predominante en las publicaciones. Se desea que una revista científica biomédica tenga, en más de la mitad de sus páginas, artículos originales. Objetivo: Describir las características generales y editoriales, y la producción científica, de las revistas biomédicas peruanas indexadas en Latindex-Perú a partir de 2015. Métodos: Estudio descriptivo transversal. Se incluyeron revistas peruanas de Ciencias de la Salud encontradas en el directorio Sistema Regional de Información en Línea para Revistas Científicas de América Latina, el Caribe, España y Portugal (Latindex). La población estuvo formada por 44 revistas científicas biomédicas peruanas, con temática Ciencias de la Salud (medicina humana, odontología, enfermería, farmacia y bioquímica). El listado de estas se obtuvo mediante el motor de búsquedas avanzadas de Latindex. Resultados: Se describieron características generales: localización, tipo de organización editora, periodicidad, formato de publicación de los artículos, uso de DOI y OJS, revisión por pares y h-index. El 54,4 por ciento de las revistas tuvo su organización encargada en una universidad y el 86,3 por ciento utilizó el OJS. La sede editorial del 68,18 por ciento de las revistas fue Lima. Conclusiones: Las revistas presentan una tendencia a adaptarse al OJS, publican principalmente artículos originales y casos clínicos, y utilizan la revisión por pares como criterio de calidad editorial(AU)
Introduction: Currently, there are no studies for assessing, specifically, the status of Peruvian biomedical journals based on criteria such as the use of editorial process software or the predominant type of articles in the publications. It is desired that a biomedical journal has, in more than half of its pages, original articles. Objective: To describe the general and editorial characteristics, as well as the scientific production, of the Peruvian biomedical journals indexed in Latindex-Peru as of 2015. Methods: Descriptive and cross-sectional study. Peruvian health sciences journals were included, from the Regional Cooperative Online Information System for Scholarly Journals from Latin America, the Caribbean, Spain and Portugal (Latindex). The population was made up of 44 Peruvian biomedical journals, under the topic health sciences (human medicine, dental medicine, nursing, pharmacy and biochemistry). The list of these was obtained through the Latindex advanced search engine. Results: General characteristics were described: location, type of publishing organization, periodicity, article publication format, use of DOI and OJS, peer review and h-index. 54.4 percent of the journals had a university as their responsible and 86.3 percent used OJS. The editorial venue of 68.18 percent of the journals was in Lima. Conclusions: The journals have a tendency to adapt to OJS. They publish mainly original articles and clinical cases, and use peer review as a criterion for editorial quality(AU)
